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5/28/10

Immune System Troubles Could Spark Behavior Woes

Fixing gene connected to immune system cured 'hair-pulling' disorder in mice, study found

In the first scientific illustration of exactly how some psychiatric illnesses might be linked to an immune system gone awry, researchers report they cured mice of an obsessive-compulsive condition known as "hair-pulling disorder" by tweaking the rodents' immune systems.

Although scientists have noticed a link between the immune system and psychiatric illnesses, this is the first evidence of a cause-and-effect relationship, said the authors of a study appearing in the May 28 issue of the journal Cell. The "cure" in this case was a bone marrow transplant, which replaced a defective gene with a normal one.

The excitement lies in the fact that this could open the way to new treatments for different mental disorders, although bone marrow transplants, which can be life-threatening in themselves, are not a likely candidate, at least not at this point.

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HealthDay News
By Amanda Gardner
May 27, 2010

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